MSI PRO B660M-B DDR4 w/ DDR4-4600(OC), 7.1 Audio, M.2 PCIe 4, 2.5G LAN

MX00122965 PRO B660M-B DDR4 w/ DDR4-4600(OC), 7.1 Audio, M.2 PCIe 4, 2.5G LAN
MX00122965 PRO B660M-B DDR4 w/ DDR4-4600(OC), 7.1 Audio, M.2 PCIe 4, 2.5G LAN MX00122965 PRO B660M-B DDR4 w/ DDR4-4600(OC), 7.1 Audio, M.2 PCIe 4, 2.5G LAN MX00122965 PRO B660M-B DDR4 w/ DDR4-4600(OC), 7.1 Audio, M.2 PCIe 4, 2.5G LAN MX00122965 PRO B660M-B DDR4 w/ DDR4-4600(OC), 7.1 Audio, M.2 PCIe 4, 2.5G LAN

Product Info

MSI's PRO B660M-B DDR4 Motherboard

PRO Series

PRO series helps users work smarter by delivering an efficient and productive experience. Featuring stable functionality and high-quality assembly, PRO series motherboards provide not only optimized professional workflows but also less troubleshooting and longevity.

  • Supports 12th Gen Intel® Core™, Pentium® Gold and Celeron® processors for LGA 1700 socket
  • Supports DDR4 Memory, up to 4600+(OC) MHz
  • Core Boost : With premium layout and digital power design to support more cores and provide better performance
  • Memory Boost: Advanced technology to deliver pure data signals for the best performance, stability and compatibility
  • Lightning Fast Experience: PCIe 4.0, Lightning Gen4 x4 M.2 with M.2 Shield Frozr
  • 2.5G LAN: Upgraded network solution for professional and multimedia use. Delivers a secure, stable and fast network connection
  • Audio Boost: Reward your ears with studio grade sound quality
  • Steel Armor: Protecting VGA cards against bending and EMI for better performance, stability and strength.



MSI motherboards feature tons of convenient and smart design for DIY users, countless system tuning and troubleshooting tools are at your disposal to push your system to new heights and satisfy even the most demanding tweaker. Makes it so easy to install your own motherboard without any issue.


With more cores' processors, thermal and power design is more important to make sure the temperature keeps lower. MSI extended PWM heatsink with 7W/mK thermal pad ensures even high-end processors to run in full speed with MSI motherboards.

M.2 Shield Frozr
World's fastest SSDs can start to lower performance when getting hot. Part of the motherboards heatsink design, M.2 SHIELD FROZR is the next generation M.2 thermal solution to avoid this by offering the best thermal protection to make sure that SSD maintains maximum performance.

Frozr AI Cooling
Detecting CPU & GPU temperatures and automatically adjusting fan duty of system fans to a proper value by adopting MSI AI ENGINE in the correct Peformance, Silent and Manual Modes.

MSI motherboards let you manage speeds and temperatures for all your system and CPU fans. Total Fan Control allows you check your primary system characteristics in a simplified graphical interface. You can also set up to 4 temperature targets for CPU and motherboard, which will adjust the fan speeds automatically.

Designed to support the most popular All-In-One & customized water cooling solutions on the market, a dedicated water pump PIN header gives you full control of the water pump speed. A clearly marked "keep-out-zone" allows for easy and safe installation and a perfect fit.


EZ M.2 Clip
Have trouble turning screws? MSI innovative EZ M.2 clip assist you install an M.2 SSD quickly and effortlessly.

Ran into trouble? Onboard LEDs for key components will indicate the source of the problem so you know exactly where to look to get it up and running again.

Reliable Components

PCB Design
The PCB design has been optimized for higher bandwidth and faster transfer speeds, which is also beneficial for reliable circuit transmission.

The most important part of DIY design is expandibility. MSI Pro Motherboards feature plenty of options that Prosumers want and need; Stable LAN, Faster Storage, Faster USB transfers and expandable connectors that are ready to increase your limits.

2.5Gbps LAN provides incredible data transfer speed faster than general Gigabit LAN. This is a premium solution for demanding users.

MSI LAN Manager automatically classifies and prioritizes the latency-sensitive applications, giving you the best online experience with low latency.


  • Allows you to change application traffic priority
  • Allows you to customize bandwidth for each application

Lightning Gen 4

Fast Future-Ready Storage
MSI PRO series motherboards support all the latest storage standards, which allows users to connect any ultra-fast storage device. Higher efficiency makes your work easier.

Lightning Gen 4 PCIe
MSI lightning Gen 4 PCI-E is the latest and the fastest PCI-E data transfer solution with 64GB/s of transfer bandwidth that has doubled compared to its previous generation. PCIe 4.0 maintains both backward and forward compatibility with older and newer specifications.

Lightning Gen 4 M.2
Utilizing 12th Gen Intel® Core™ processors, MSI B660 PRO Motherboards feature latest Lightning Gen 4 M.2 which is the fastest onboard storage solution on the market with up to 64 Gb/s transfer speeds.

Optane: Boost Your HDD to Perform Like a SSD
PC Enthusiasts can now enjoy the performance of an SSD on their HDD by coupling it with the new Intel® Optane™ Memory device. Intel® Optane™ technology provides an unparalleled combination of high throughput, low latency, high quality of service, and high endurance.

2.5Gbps LAN provides incredible data transfer speed faster than general Gigabit LAN. This is a premium solution for demanding users.

Add more color if you want! Mystic Light Extension pin header provides an intuitive way to control additional RGB strips and other RGB peripherals added to a system, without needing a separate RGB controller.


Memory Boost & XMP
MSI OC LAB does not merely work hard on extreme overclocking. The XMP memory profile has great improvement on performance and efficiency for B660. Easy to enable XMP profile with auto power settings to get the best memory speed and stability.

Core Boost
Core Boost technology combines MSI's premium layout and optimized power design which allows for faster and undistorted current delivery to the CPU at pin-point precision. Not only supporting multi-core CPU, also creating the perfect conditions for your CPU overclocking.


Audio Boost

  • Dedicated High Definition Audio Processor
    Make sure you enjoy the purest sound quality in both stereo and surround sound
  • High Quality Audio Capacitors
    A high fidelity sound experience with exceptional acoustics and realism for studio level headphones is ensured
  • HD Audio Connectors
    Keep you sound perfect by transmit your audio with pure digital signal

Isolated Audio Signal

  • Isolated Audio Design - Like a dedicated sound card, audio components and circuits have been laid on a reserved motherboard section and electrically isolated.
  • Separated audio layers for clean left & right channels - Using separated layers in the PCB ensures equally pristine sound quality for both left and right audio channels.

De-Pop Protection

Audio Boost protects your ears by eliminating those annoying loud popping sounds when you plug/unplug devices or turn your PC on/off.

Bios & Software

MSI Center
MSI brand new MSI Center unifies a suite of MSI software utilities into a single centralized application. Take control of advanced motherboards features and unleash endless possibilities.

Click Bios 5
Get more from a loaded BIOS designed for ease of use. Fine-tune the motherboard for gaming performance, efficiency, or overclocking world records!

    Quickly overclock your CPU with a single button for more performance
  • XMP
    Choose from a preset XMP profile and automatically overclock compatible DDR memory
    Conveniently flash or upgrade the BIOS in a few minutes from the CMOS Setup Utility
    Get immediate access to your critical hardware information in real-time including temperature, memory capacity, clock speed, and voltage
    Get extreme speed out of your system memory and get more performance
    A permanent search & favorite option in the top right corner moves you through the BIOS menus quickly

Resizable BAR (Re-Size BAR) is an advanced PCI Express feature that enables the CPU to access the entire GPU frame buffer at once and improve performance.


System Safety
All MSI PRO series motherboards have SECURITY function in BIOS to protect every private files for no matter business or daily use.

Secure Boot
Secure boot is a security standard to make sure that a device boots using only software that is trusted. When the PC starts, the firmware checks the signature of each piece of boot software, including UEFI firmware drivers, EFI applications, and the operating system. The PC boots while the signatures are valid.

Additional Information:

Visit the Manufacturer Web Page for Full Details

System Requirements

  • Windows® 11 / 10, 64-bit


Make and Model MSI PRO B660M-B DDR4 mATX Motherboard
CPU Supports 12th Gen Intel® Core™ Processors
Supports processor socket LGA1700
See supported processors
Chipset Intel® B660 Chipset
Memory 2x DDR4 memory slots, support up to 64 GB1

4600(OC) , 4400(OC) , 4266(OC) , 4200(OC) , 4000(OC) , 3800(OC) , 3733(OC) , 3600(OC) , 3466(OC) , 3400(OC) , 3333(OC) , 3200(JEDEC) , 2933(JEDEC) , 2666(JEDEC) , 2400(JEDEC) , 2133(JEDEC) MHz
1. Please refer to for more information on compatible memory.
See supported memory

Expansion Slots 1x PCIe v4.0 x16 slot
1x PCIe 3.0 x1 slots
Multi-GPU Support Supports AMD® CrossFire™ Technology
Onboard Graphics Support 4K@60Hz as specified in HDMI 2.1, VGA – Requires Processor Graphics
RAID Supports RAID 0, RAID 1, RAID 5 and RAID 10 for SATA storage devices
Storage 1x M.2 Gen4 x4 64Gbps slot
USB 6x USB 3.2 Gen 1 5Gbps (6 Type-A)
6x USB 2.0
LAN Realtek® RTL8125BG 2.5G LAN
Wireless Communication None
Audio 8-Channel (7.1) HD Audio with Audio Boost
Back Panel I/O VGA
Keyboard / Mouse
LAN port
Audio connector
USB 2.0
USB 3.2 Gen 1 5Gbps Type-A
Internal I/O Connectors 1x 24-pin ATX main power connector
1x 8-pin ATX 12V power connector
4x SATA 6Gb/s connectors
2x USB 2.0 connector (support additional 4 USB ports)
1x USB 3.2 Gen 1 5Gbps connector (support additional 2 USB ports)
1x 4-pin CPU fan connector
2x 4-pin system fan connectorx
1x Front panel audio connector
2x System panel connectors
1x Serial port connector
1x TPM module connector
1x Chassis Intrusion connector
1x Clear CMOS jumper
1x Tuning Controller Connector
Operating System Windows® 11, 10 64-bit
BIOS Features 1x 256 Mb flash
ACPI 6.4, SMBIOS 3.4
Hardware Monitor CPU / System / Chipset Temperature Detection
CPU / System / Pump Fan Speed Detection
CPU / System / Pump Fan Speed Control
Form Factor Micro ATX
Dimensions (LxW) 9.6 in. x 8.7 in. (24.4 cm x 22.0 cm)
Weight N/A